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Chili Pepper and Marijuana Calm the Gut

Chili Pepper and Marijuana Calm the Gut

| Kim Krieger

You wouldn’t think chili peppers and marijuana have much in common. But when eaten, both interact with the same receptor in our stomachs, according to a paper by UConn researchers published in the April 24 issue of the journal Proceedings of the National Academy of Sciences. The research could lead to new therapies for diabetes and colitis, and opens up intriguing questions about the relationship between the immune system, the gut, and the brain.

Touch a chili pepper to your mouth and you feel heat. And biochemically, you aren’t wrong. The capsaicin chemical in the pepper binds to a receptor that triggers a nerve that fires off to your brain: hot! Those same receptors are found throughout the gastrointestinal tract, for reasons that have been mysterious.

Chili Pepper and Marijuana Calm the Gut






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